Development of focal segmental glomerulosclerosis in a patient with polycythemia vera: can polycythemia vera be a cause of focal segmental glomerulosclerosis?

Focal segmental glomerulosclerosis in a patient with polycythemia rubra vera.

A patient with polycythaemia vera associated with membranoproliferative glomerulonephritis.

Myeloproliferative disorders (MPDs) are clonal disorders of the haematopoietic stem cells. These are classified as polycythaemia vera (PV), essential thrombocythaemia (ET), chronic myeloid leukaemia (CML) and myelofibrosis (MF) depending on the main haematopoietic lineage involved. Glomerulonephritis (GN) refers to a pattern of glomerular injury based on characteristic histopathology findings. ...

Complex Arterial and Venous Thrombosis in Polycythemia Vera: what Does Leukocytosis Predict?

Thromboembolic events represent the main cause of morbidity and mortality in patients with polycythemia vera. Leukocytosis has been identified as an important risk factor for development of vascular thrombosis. A 47-year-old woman with polycythemia vera presented with pain and swelling in her right calf. She was scheduled to receive anagrelide which was effective on polycythemia and thrombocyto...

POEMS syndrome, calciphylaxis and focal segmental glomerulosclerosis – VEGF as a possible link

BACKGROUND Polyneuropathy organomegaly endocrinopathy M-protein skin changes (POEMS) syndrome is a rare cause of polyneuropathy. Calciphylaxis, a severe disease leading to necrotic ulcers of the skin, is associated with POEMS syndrome and also with renal disease. This case report describes a patient with POEMS syndrome plus primary focal segmental glomerulosclerosis. CASE PRESENTATION A 27-ye...

A Case Report of Schimke Immuno-Osseous Dysplasia: A Rare Autosomal Recessive Disorder

      Schimke immune-osseous dysplasia (SIOD) is a rare autosomal recessive disorder presented with specific facial features, skeletal dysplasia, steroid resistance nephrotic syndrome (SRNS) and cellular immune insufficiency. This is a SIOD case reported from Iran. He was 5 years old boy when evaluated for proteinuria and short stature. In appearance, we detected hyperpigmented macules, kyphosc...